Atherosclerosis is a very complex disease of the arterial wall that leads to narrowing and obstruction of the artery. Basically the narrowing is due to the sclerotic deformation of the artery and the development of raised patches called atherosclerotic plaques in the inner lining of the arterial wall. Depending on which organ in the body the artery feeds, atherosclerosis in its walls will impair the blood flow to that organ.
Injury to the inside lining of vessels (endothelium) begins with the process of inflammation. From the beginning to the very end of the formation of every atherosclerotic plaque in your blood vessels is inflammation. The universal marker for an ongoing inflammation in the body, called C-reactive protein, is rapidly becoming accepted as the best marker for atherosclerosis and for predicting its deadly complications: heart attacks and strokes.